Figure 2
From: Crystal structure of subunit VPS25 of the endosomal trafficking complex ESCRT-II
Structure based sequence alignment of Vps25. Sequences aligned using S. cerevisiae Vps25 (gene bank #CAA89632) and Vps25 orthologues from H. sapiens (#BE386260), D. melanogaster (#AAF59066) and from C. elegans (#T26073). Identical residues are shown on red background, similar residues are drawn in red and sequence similarity is underlined by blue boxes. Secondary structure elements are shown. Disordered regions in the Vps25 structure are indicated by dashed lines.