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Table 1 Analysis of the Ramachandran plot and identity between template and models of NS3 protease variants. The accuracy of comparative modeling is related to the percentage of sequence identity on which the model is based, correlating with the relationship between the structural and sequence similarities of two proteins. High accuracy comparative models are based on >50% sequence identity to their templates. They tend to have ~1 Å r.m.s. error for the main-chain atoms, which is comparable to the accuracy of a medium-resolution NMR structure or a low-relosution X-ray structure. All structure models in the database were generated using alignments with more than 79% sequence identity, which generating models with high accuracy.

From: Molecular models of NS3 protease variants of the Hepatitis C virus

Genbank access code Residue Range Identity (%) Region of the Ramachandran plot (%)
    Most Favorable Additional Allowed Generously Allowed Disallowed
AJ238800 1027 – 1657 95.0 94.9 5.1 0.0 0.0
AJ238799 1027 – 1657 95.7 95.1 4.6 0.2 0.2
AF139594 1028 – 1658 95.7 95.8 3.8 0.2 0.2
D17763 1033 – 1663 80.5 94.9 4.9 0.2 0.0
AF054247 1027 – 1657 94.0 95.0 4.8 0.2 0.0
AF054248 1027 – 1657 93.8 94.9 5.1 0.0 0.0
AF054249 1027 – 1657 93.8 95.2 4.8 0.0 0.0
D50409 1031 – 1661 80.3 95.1 4.9 0.0 0.0
D84262 1032 – 1662 84.2 95.0 5.0 0.0 0.0
D84263 1025 – 1665 83.1 95.2 4.8 0.0 0.0
D84264 1029 – 1659 83.9 95.2 4.8 0.0 0.0
D84265 1027 – 1657 82.5 94.9 5.1 0.0 0.0
D10749 1027 – 1657 90.5 94.9 5.1 0.0 0.0
D13558 1027 – 1657 94.1 94.8 5.2 0.0 0.0
D14853 1027 – 1657 88.8 95.3 4.7 0.0 0.0
D00944 1031 – 1661 79.8 95.1 4.9 0.0 0.0
D10988 1031 – 1661 79.7 95.1 4.9 0.0 0.0
AF046866 1033 – 1663 80.3 94.7 5.1 0.2 0.0
D49374 1035 – 1665 79.8 94.7 5.1 0.2 0.0
Y11604 1027 – 1657 84.7 95.4 4.6 0.0 0.0
Y13184 1028 – 1658 82.3 95.2 4.8 0.0 0.0
Y12083 1031 – 1661 81.9 94.6 5.2 0.0 0.2
U16362 1027 – 1657 92.6 95.2 4.6 0.2 0.0
U45476 1027 – 1657 94.7 94.9 5.1 0.0 0.0
AJ000009 1027 – 1657 95.2 95.1 4.9 0.0 0.0
M67463 1027 – 1657 89.6 94.9 4.9 0.2 0.0
D63822 1031 – 1661 79.2 95.2 4.8 0.0 0.0
D63821 1032 – 1662 79.1 94.7 5.1 0.2 0.0
D14484 1027 – 1657 94.3 95.8 4.2 0.0 0.0
D11168 1027 – 1657 94.9 95.0 5.0 0.0 0.0
D11355 1027 – 1657 94.6 95.0 5.0 0.0 0.0
D50480 1027 – 1657 93.5 95.0 5.0 0.0 0.0
D50481 1027 – 1657 94.6 95.4 4.6 0.0 0.0
D50482 1027 – 1657 94.7 95.5 4.3 0.2 0.0
D50483 1027 – 1657 93.6 95.2 4.8 0.0 0.0
D50485 1027 – 1657 94.3 95.6 4.4 0.0 0.0
D50484 1027 – 1657 94.1 95.3 4.7 0.0 0.0
D28917 1033 – 1663 80.5 95.2 4.6 0.2 0.0
D30613 1027 – 1657 93.8 95.4 4.6 0.0 0.0
D10934 1027 – 1657 95.2 95.3 4.7 0.0 0.0
AF207762 1027 – 1657 94.0 95.1 4.9 0.0 0.0