Figure 3
From: Structural organization and interactions of transmembrane domains in tetraspanin proteins
Helical wheel diagrams of transmembrane domains TM1-4 reflecting the consensus residue types. The color scheme is as in Figure 1. The numbers refer to CD9 sequence. Heptad positions a through g are indicated for TM1-3. A predicted interaction between positions a and e in TM1 and a and d in TM2 is shown by dotted lines (see Figure 6 and text for details). Arrows reflect the efficiency of intermolecular cross-linking via single cysteines placed in these positions (see Figure 7 and text for details).