Ala scan (Kv2.1) | Published V50 (mV) | Predicted V50 (mV) | Wild type (mV) |
---|
L97A
| 0.6 | -7.23 | -4.9 |
*I100A
| -7.3 | -7.23 | -4.9 |
L117A
| -1.6 | -7.23 | -4.9 |
*V125A
| -4.6 | -7.23 | -4.9 |
L135A
| 1.5 | -7.23 | -4.9 |
A154Y
| 7 | 27.5 | -4.9 |
MAE
|
7.5
|
- The V50 predictions for a set of published alanine scanning mutants are compared to the published measured V50 values. The residues marked with * are residues in which an alanine exists at this position in at least one of the channels in the training dataset.