Figure 1From: Prediction of "hot spots" of aggregation in disease-linked polypeptidesAggregation profile of natively unfolded proteins related to disease. The average aggregation propensity of the different polypeptides is shown as a dashed line. Minimal protein regions which have been experimentally proven to be involved in aggregation are shown at the top of the plot as black bars. Regions in the core of the fibrils are shown as grey bars (when information available). The NAC fragment of α-Synuclein is shown as a dashed bar.Back to article page