Figure 5
From: Similar folds with different stabilization mechanisms: the cases of prion and doppel proteins
Principal Eigenvector Components. The components of the eigenvectors associated with the largest eigenvalue from the energy decomposition analysis in the all-atom MD simulations for (a; left panel) the PrP protein and (b; right panel) the Dpl protein at different temperatures, reported in each single panel. The broken horizontal line depicts the threshold value as calculated in equation (3) in Methods. In the top panels, the secondary structural elements are reported in correspondence to residue numbers: circles represent α-helical and squares represent β-sheet structures.