Figure 1From: The crystal structure of superoxide dismutase from Plasmodium falciparumSequence alignment of FeSOD from P. falciparum and E.coli and MnSOD from the human mitochondrion. Identical residues are highlighted with a red background and similar residues are boxed. Pf FeSOD (top) and MnSOD (PDB code 1n0j [36] bottom) secondary structure elements are indicated. Residues predicted to be specific to MnSOD sequences [37] are marked with a triangle. Note the similarity of secondary structure between the two types of SOD. The longer helices in the N-terminal domain of MnSOD contribute to tetramer formation. The figure was made using ESPript [38].Back to article page