Figure 3

Structural details of the Asf1N-H3a3 interface. (A) Schematic of the interactions between Asf1 and H3α3. Asf1 residues are displayed in yellow, H3α3 in blue. Yeast-specific residues on Asf1 and H3α3 are underlined. Ion pair and hydrogen bonding interactions measuring 3.3 Å or less are represented as dashed lines. Van der Waals interactions are shown as gold arcs. (B) Alignment of Asf1 and H3 residues involved in the interaction across several eukaryotes. Residues participating in the interaction are boxed, with yeast specific Asf1 residues highlighted in yellow and H3-Leu130 highlighted in blue. ClustalW was used to generate the Asf1 alignment.