System description | Crystal structure used for construction | Residue span | pY-peptide binding cleft state in crystal †| Abbreviation for system |
---|---|---|---|---|
Isolated N-SH2 | Isolated N-SH2 [PDB:1AYD] | 1–108 | Open | 1AYD:N-SH2 |
Isolated N-SH2 | Full SHP-2 [PDB:2SHP] | 1–108 | Closed | 2SHP:N-SH2 |
Full SHP-2 | Full SHP-2 [PDB:2SHP] | 1–525 | Closed | 2SHP:SHP-2 |