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Figure 5 | BMC Structural Biology

Figure 5

From: The high-resolution NMR structure of the R21A Spc-SH3:P41 complex: Understanding the determinants of binding affinity by comparison with Abl-SH3

Figure 5

Chemical shift perturbations resulting from the binding of p41 to R21A Spc-SH3. Left panel: The finger-print region of the different TOCSY spectra recorded for the six titration points with p41. From black to dark blue the p41 concentration is increased. Only Cα H-NH cross-peaks are indicated. Right panel: Chemical shift perturbations for all protons >0.1 ppm (green balls) derived from the TOCSY experiments, mapped on a model of the complex of α-spectrin SH3 (red) with p41 (blue spheres) obtained from super-position on the Abl-SH3:P41 complex.

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