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Table 3 Thermodynamic parameters governing PTS1 peptide binding to Pex5p(C).

From: A previously unobserved conformation for the human Pex5p receptor suggests roles for intrinsic flexibility and rigid domain motions in ligand binding

peptide

nb

ΔH (kJ/mol)

-TΔS (kJ/mol)

ΔG(kJ/mol)

Kd (nM)

PGNAKL a

1.00

-45.1

8.7

-36.4

664 ± 37

YQSKL

1.00

-63.1

25.5

-37.6

429 ± 12

  1. aData from [9].
  2. bn = stoichiometry
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BMC Structural Biology

ISSN: 1472-6807

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