Figure 7
The binding of 2-ketobutyrate to TdcF. Schematic representation of the binding of 2-ketobutyrate to TdcF. 2-ketobutyrate is shown in red, whilst residues from one subunit are in green and those from the other subunit are in blue; darker colours indicate residues in the foreground and paler colours are used for those residues in the background. Underlining indicates strictly conserved residues in the YjgF/YER057c/UK114 family [8]. Important hydrogen bonds are shown as dashed lines and the curved magenta lines indicate non-bonding interactions with the ligand. The numbers in red give average hydrogen bond lengths in Å. Water molecules are indicated by the letter "W". The cluster of water molecules to the right of the ligand is in direct contact with bulk solvent. The view is similar to that seen in Figures 3–5.