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Figure 8 | BMC Structural Biology

Figure 8

From: Binding induced conformational changes of proteins correlate with their intrinsic fluctuations: a case study of antibodies

Figure 8

Comparison of global modes with the real displacements for the SPE7 antibody. Dashed lines are for the experimental displacements. Solid lines represent the residue fluctuations for the first and second global modes, respectively (Parts A and B). The insets are the crystal structures of SPE7. The top structures are for the unbound conformers (1oaq and 1ocw). The lower panel shows the bound conformations (1oau and 1oaz). The purple highlighted regions are the antigen binding regions.

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