Calculated membrane binding modes for kalata-B1 plant toxin from cyclotide family (A) and cobra P-type cardiotoxin (B). The backbone of two proteins is shown in ribbon model. Micelle-embedded residues identified by solution NMR are colored red. Hydrocarbon core boundary at the extracellular side is indicated by red dots. The layer of lipid phosphates ("P") located 5 Å outside the hydrocarbon boundary is indicated by gold dots, the center of membrane located 15 Å inside the boundary is indicated by grey dots.