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Figure 2 | BMC Structural Biology

Figure 2

From: Crystal structure of vaccinia virus uracil-DNA glycosylase reveals dimeric assembly

Figure 2

Ribbon model of vvUDG. (A) Monomer of vvUDG. The figure depicts a ribbon model of vvUDG. The secondary structure elements are labeled according to Fig. 1A. Helices are labeled α1 through α10 and strands are marked β1 through β10. The active site residues are displayed as stick models. Positions of ts mutations are also shown as stick models (color code: purple). (B) Type I dimer of vvUDG. The figure shows the type I dimer of vvUDG as observed in the asymmetric unit of the trigonal crystal form. The subunits (A and B) in this dimer are related by NCS. Active site residues and ts mutation site residues are shown as stick models as seen in (A). (C) Type II dimer of vvUDG. The figure shows the type II dimer of vvUDG. These dimers are observed in the asymmetric unit of the orthorhombic crystal form (subunits related by NCS) and also in the unit cell of the trigonal crystal form (subunits related by crystallographic symmetry). The active site residues are displayed as stick models. Positions of ts mutations are also shown as stick models (color code: purple).

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