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Figure 5 | BMC Structural Biology

Figure 5

From: Computational modeling of protein mutant stability: analysis and optimization of statistical potentials and structural features reveal insights into prediction model development

Figure 5

Prediction efficiency of structural training datasets & Gaussian apodization – Correlation for predicting mutations with thermal ΔΔG values. Comparison of structural training datasets to render torsion angle potentials. For the atom potentials, the PISCES dataset was used as structural training dataset. For the torsion angle potentials, 3 datasets were compared: PISCES, SCOP-ASTRAL and Top500. Correlation and prediction accuracy for predicting mutations with thermal ΔΔG values. PISCES-GA and PISCES denote respectively, the datasets used with and without Gaussian apodization.

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BMC Structural Biology

ISSN: 1472-6807

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