Figure 5

Binding interface of H4-AcK12 peptide on Brd2 BD2. (A) A histogram view of combined chemical shift perturbations of Brd2 BD2 by addition of H4-AcK12 peptide. The mean value is denoted as a solid line and the mean value plus one standard deviation as a dash line. (B) A ribbon diagram view mapping the binding interface of H4-AcK12 peptide on Brd2 BD2. The residues, whose combined chemical shift changes were more than the mean value plus one standard deviation and above the mean value, are colored in blue and cyan respectively. The figure B was generated in PyMOL.