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Table 1 Structural statistics for the selected 20 structures of Brd2 BD2a

From: Solution structure of the second bromodomain of Brd2 and its specific interaction with acetylated histone tails

Number of NMR restraints used in the structure calculation
   Intra-residue 563
   Sequential (|i-j| = 1) 573
   Medium-range (|i-j|<5) 475
   Long-range (|i-j|≥5) 355
   Total NOE restraints 1966
   Hydrogen bonds 49
   Dihedral angle restraints 146
Lennard-Jones potential energy (kcal mol-1) -360.86 ± 15.49
RMSD from idealized covalent geometry  
   Bonds (Å) 0.0010 ± 0.00002
   Angles (deg) 0.2878 ± 0.0016
   Impropers (deg) 0.0972 ± 0.0038
RMSD from experimental restraints  
   Distance (Å) 0.0037 ± 0.0005
   cdih (deg) 0.0436 ± 0.0214
Coordinate RMSD from mean (Å) residues 302 to 406  
   All backbone atoms 0.69
   All heavy atoms 1.18
Secondary structure elementsb  
   All backbone atoms 0.58
   All heavy atoms 1.07
Ramachandran plot (% residues)  
   Residues in most favored regions 87.0
   Residues in additional allowed regions 10.3
   Residues in generously allowed regions 2.5
   Residues in disallowed regions 0.2
  1. a None of the structure exhibits distance violations greater than 0.2 Å or dihedral angle violations greater than 2°.
  2. b Residues Q302-S315, A319-Y326, H337-I342, L349-N358, A364-Y381, D387-K405.