Table 1 Structural statistics for the selected 20 structures of Brd2 BD2^a

   Intra-residue

563

   Sequential (|i-j| = 1)

573

   Medium-range (|i-j|<5)

475

   Long-range (|i-j|≥5)

355

   Total NOE restraints

1966

   Hydrogen bonds

49

   Dihedral angle restraints

146

Lennard-Jones potential energy (kcal mol-1)

-360.86 ± 15.49

RMSD from idealized covalent geometry

   Bonds (Å)

0.0010 ± 0.00002

   Angles (deg)

0.2878 ± 0.0016

   Impropers (deg)

0.0972 ± 0.0038

RMSD from experimental restraints

   Distance (Å)

0.0037 ± 0.0005

   cdih (deg)

0.0436 ± 0.0214

Coordinate RMSD from mean (Å) residues 302 to 406

   All backbone atoms

0.69

   All heavy atoms

1.18

Secondary structure elements^b

   All backbone atoms

0.58

   All heavy atoms

1.07

Ramachandran plot (% residues)

   Residues in most favored regions

87.0

   Residues in additional allowed regions

10.3

   Residues in generously allowed regions

2.5

   Residues in disallowed regions

0.2