Structural disorder promotes assembly of protein complexes

BMC Structural Biology

Table 2 Number of singular proteins and proteins in complexes of different sizes in the different data sets

Complex size	Yeast (Gavin06)	E. coli (Arifuzzaman06)	E. coli (Butland05)	E. coli (Gully06)
singular proteins	241
2 – 4 proteins	346	1446	367	322
5 – 10 proteins	650	1573	226	441
11 – 20 proteins	789	827	186	382
21 – 30 proteins	647	187	194	325
31 – 100 proteins	747	57	128	245

For yeast, those proteins were deemed singular for which no binding partners have been found in each study (they were not cross-checked against each other). For E. coli, those proteins in Swiss-Prot were deemed singular (altogether 1922 proteins), for which neither in IntAct nor in the Swiss-Prot annotation lines did we find any evidence of complex-forming.

ISSN: 1472-6807