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Figure 6 | BMC Structural Biology

Figure 6

From: The structure of Mycobacteria 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase, an essential enzyme, provides a platform for drug discovery

Figure 6

Stereo-view of the active site overlay of Ms IspF and Ec IspF. Residues from Ms IspF are labeled and CDP-B is the depicted conformer. Protein atoms are colored: C of Ms IspF green, C of Ec IspF wheat, all N atoms blue, O atoms red, and Se atoms magenta. The marine sphere depicts the water molecule that contributes to solvent-mediated interactions between IspF and the ribose hydroxyls of CDP.

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