Figure 4From: Distinct energetics and closing pathways for DNA polymerase β with 8-oxoG template and different incoming nucleotidesThe resolved free energy profiles. The free energy profiles of the 8-oxoG:dC TP and 8-oxoG:dA TP complexes during pol β's thumb closing. The superimposed dashed lines are approximate free energy profiles of nonlesioned G:C (blue) and G:A (magenta) systems [32], respectively.Back to article page