Skip to main content

Table 2 Energetics of ligands binding to RTA.

From: Fragment-based identification of determinants of conformational and spectroscopic change at the ricin active site

Compound

K D (M) a

ΔG° (kJ/mol) a

ΔH° (kJ/mol)

ΔS° (kJ/(K*mol))

Urea

0.5 ± 0.09

-2 ± 0.6

-13 ± 2

-0.04 ± 0.01

N-methylurea

0.9 ± 0.04

-0.2 ± 0.09

---

---

Acetamide

1.4 ± 0.03

0.8 ± 0.06

---

---

Formamide

0.9 ± 0.1

0 ± 0.3

---

---

Adenine

(7 ± 0.5) × 10-4

-20 ± 0.6

-53 ± 3

-0.12 ± 0.01

  1. a Results are the average and standard error of three measurements.
Back to article page

BMC Structural Biology

ISSN: 1472-6807

Contact us