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Figure 7 | BMC Structural Biology

Figure 7

From: Using molecular principal axes for structural comparison: determining the tertiary changes of a FAB antibody domain induced by antigenic binding

Figure 7

A. The Displacements of the amino acid centroids from their locations in the unliganded domain of the heavy chain (PDB file, 1HIL) to their locations in the complexed domain of the heavy chain (PDB file, 1IFH). B. The Displacements described in A, shown on an expanded scale about the amino acid residues of greatest Displacement. C. The differences in the ellipsoidal distances (Differential Ellipsoidal Distances) of the amino acid centroids of the heavy chain domain of the complex (PDB, 1IFH) from their values in the uncomplexed heavy chain domain (PDB, 1HIL). D. The differences described in C, shown on an expanded scale about the amino acid residues showing the greatest differences.

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