Example of completely reverse non-sequential alignment. Structures of adenylate kinase (PDB-code 1ki9:A, shown on a) and glucose/galactose-binding protein (PDB-code 1gca, show on b) have been aligned by TOPOFIT with N
/RMSD of 85/1.5 Å. Alignment segments are shown by different colors. In each segment the order of residues is different in the compared protein. c) displays the corresponding alignment plot. d) displays a schematic linear diagram of segment permutation in the alignment.