Figure 5
From: Neutral evolution of Protein-protein interactions: a computational study using simple models
The population dynamics enhance robustness and functionality. A) The distribution of mutational robustness n for a given 2D protein dimer. Solid line: the steady state population. Dashed line: a population drawn randomly from the neutral network. B) Idem for the 3D, off-lattice Grb2-Vav 3D dimer. C) The folding temperature distribution for the same 2D dimer; solid line: steady state population; dashed line: random population. D) The distribution of the equilibrium concentration [AB]func of the functional dimer, for the same 2D dimer; solid line: steady state population; dashed line: random population.