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Figure 1 | BMC Structural Biology

Figure 1

From: Structural analysis of the carboxy terminal PH domain of pleckstrin bound to D-myo-inositol 1,2,3,5,6-pentakisphosphate

Figure 1

Effects of IP 6 on the Binding of C-PH to LUVs containing PtdIns(3,4) P 2 . C-PH binding to LUVs was tested as follows: lane 1, total C-PH added to incubations (0.3 μM); lane 2, C-PH bound to LUVs containing only phosphatidylcholine; lane 3, C-PH bound to LUVs also containing 5 mol% PtdIns(3,4)P2 ; lanes 4–7, as lane 3 with increasing concentrations of IP6 (3, 10, 30 and 100 μM).

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