Figure 5

Conserved binding positions of inositol phosphates to PH domains. Superimposed inositol phosphates in complex with PH domains from five different proteins: DAPP1/PHISH-Ins(1,3,4,5)P₄, red, 1FAO; Grp1-Ins(1,3,4,5)P₄, yellow, 1FGY; ARNO-Ins(1,3,4,5)P₄, blue, 1U27; Grp1-Ins(1,3,4,5,6)P₅, green, 1FHW; C-PH-Ins(1,2,3,5,6)P₅, gray, 2I5F. The four conserved phosphate binding positions are boxed.