Figure 7From: Structural analysis of inhibition of E. coli methionine aminopeptidase: implication of loop adaptability in selective inhibition of bacterial enzymesStructural comparison between E. coli MetAP and human MetAPs. Structure of E. coli MetAP used in the overlays is the one complexed with 4 and coloured grey. (A) Overlay with human type I MetAP (PDB code 2NQ7) that is coloured cyan for the catalytic domain and blue for the N-terminal extension. (B) Overlay with human type II MetAP (PDB code 1B59) that is coloured magenta for the catalytic domain, orange for the N-terminal extension and red for the insert. (C) Schematic drawing of the domains in E. coli MetAP and human MetAPs.Back to article page