Figure 1
From: Crystal structure of human IPS-1/MAVS/VISA/Cardif caspase activation recruitment domain
Structure of the human IPS-1 CARD domain. (A) Structure of the MBP-CARD fusion structure with maltotetraose bound in the MBP binding site. (B,C,D) orthogonal views of the IPS-1 CARD domain colored from blue at the N-terminus to red at the C-terminus with Trp56 highlighted. (E,F,G) surface representations colored by electrostatic potential in the same orientations as the images above.