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Table 2 Number of possible substitutions (Nsub) in the different data sets. The numbers between parentheses are the difference between the Nsub and the Nsub of the control set.

From: Structural deformation upon protein-protein interaction: A structural alphabet approach

Structural letter Complex set Interface set Control set
A 4.3 (+ 1.3) 5.1 (+ 2.1) 3.0
a 5.2 (+ 1.1) 4.6 (+ 0.5) 4.1
V 5.7 (+ 1.0) 6.2 (+ 1.5) 4.7
W 5.6 (+ 1.6) 6.3 (+ 2.3) 4.0
Z 5.2 (+ 1.5) 5.9 (+ 2.2) 3.7
B 4.1 (+ 0.6) 4.4 (+ 0.9) 3.5
C 3.4 (+ 1.5) 3.7 (+ 1.8) 1.9
U 2.4 (+ 0.9) 2.3 (+ 0.8) 1.5
E 4.9 (+ 2.6) 5.1 (+ 2.8) 2.3
F 4.7 (+ 1.5) 3.9 (+ 0.7) 3.2
I 2.6 (+ 1.3) 2.9 (+ 1.6) 1.3
D 1.9 (+ 0.7) 2.0 (+ 0.8) 1.2
Q 2.7 (+ 1.1) 3.1 (+ 1.5) 1.6
O 3.3 (+ 1.7) 3.3 (+ 1.7) 1.6
H 2.7 (+ 0.9) 3.8 (+ 2.0) 1.8
Y 3.8 (+ 1.7) 3.5 (+ 1.4) 2.1
R 5.1 (+ 2.5) 5.5 (+ 2.9) 2.6
J 4.8 (+ 3.2) 5.9 (+ 4.3) 1.6
S 2.8 (+ 1.0) 3.4 (+ 1.6) 1.8
P 3.2 (+ 1.0) 3.8 (+ 1.6) 2.2
K 3.1 (+ 1.4) 4.2 (+ 2.5) 1.7
G 2.7 (+ 0.8) 2.8 (+ 0.9) 1.9
L 3.5 (+ 1.2) 4.7 (+ 2.4) 2.3
N 3.5 (+ 1.3) 4.8 (+ 2.6) 2.2
M 2.7 (+ 0.7) 3.2 (+ 1.2) 2.0
T 3.0 (+ 1.0) 4.0 (+ 2.0) 2.0
X 2.8 (+ 1.0) 4.3 (+ 2.5) 1.8