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Table 2 Number of possible substitutions (Nsub) in the different data sets. The numbers between parentheses are the difference between the Nsub and the Nsub of the control set.

From: Structural deformation upon protein-protein interaction: A structural alphabet approach

Structural letter

Complex set

Interface set

Control set

A

4.3 (+ 1.3)

5.1 (+ 2.1)

3.0

a

5.2 (+ 1.1)

4.6 (+ 0.5)

4.1

V

5.7 (+ 1.0)

6.2 (+ 1.5)

4.7

W

5.6 (+ 1.6)

6.3 (+ 2.3)

4.0

Z

5.2 (+ 1.5)

5.9 (+ 2.2)

3.7

B

4.1 (+ 0.6)

4.4 (+ 0.9)

3.5

C

3.4 (+ 1.5)

3.7 (+ 1.8)

1.9

U

2.4 (+ 0.9)

2.3 (+ 0.8)

1.5

E

4.9 (+ 2.6)

5.1 (+ 2.8)

2.3

F

4.7 (+ 1.5)

3.9 (+ 0.7)

3.2

I

2.6 (+ 1.3)

2.9 (+ 1.6)

1.3

D

1.9 (+ 0.7)

2.0 (+ 0.8)

1.2

Q

2.7 (+ 1.1)

3.1 (+ 1.5)

1.6

O

3.3 (+ 1.7)

3.3 (+ 1.7)

1.6

H

2.7 (+ 0.9)

3.8 (+ 2.0)

1.8

Y

3.8 (+ 1.7)

3.5 (+ 1.4)

2.1

R

5.1 (+ 2.5)

5.5 (+ 2.9)

2.6

J

4.8 (+ 3.2)

5.9 (+ 4.3)

1.6

S

2.8 (+ 1.0)

3.4 (+ 1.6)

1.8

P

3.2 (+ 1.0)

3.8 (+ 1.6)

2.2

K

3.1 (+ 1.4)

4.2 (+ 2.5)

1.7

G

2.7 (+ 0.8)

2.8 (+ 0.9)

1.9

L

3.5 (+ 1.2)

4.7 (+ 2.4)

2.3

N

3.5 (+ 1.3)

4.8 (+ 2.6)

2.2

M

2.7 (+ 0.7)

3.2 (+ 1.2)

2.0

T

3.0 (+ 1.0)

4.0 (+ 2.0)

2.0

X

2.8 (+ 1.0)

4.3 (+ 2.5)

1.8