
ACA Distributions^{+}



Structural environment

P
≤ 0.05**

Total

SCRs

αHelices in SCRs

βstrands in SCRs

All
    
Dataset A

0.0864

0.0640

0.0859

0.9437

Dataset B

0.0124

0.0069

0.0159

0.1745

ShapiroWilk Test°

0.90/0.99

0.07/0.002°°

0.96/0.59
 
Hyperthermophiles
    
Dataset A

0.0790

0.0029

0.0524

0.8120

ShapiroWilk Test°
 
0.26/0.90

0.97/0.16
 
Dataset B

0.0205

0.0001

0.0113

0.061

ShapiroWilk Test°

0.53/0.42

0.49/0.36

0.13/0.003°°°
 
Thermophiles
    
Dataset A

0.6901

0.5139

0.8387

0.7080

Dataset B

0.3357

0.7530

0.3123

0.6027

 * Values are expressed as the associated probability P of acceptance of the null hypothesis
 ** P ≤ 0.05 are considered statistically significant, and are bolded
 + The statistical significance of the observed differences of ACA between hyper/thermophilic proteins and their mesophilic counterparts
 °The obtained P(t) of the ShapiroWilk test for significant results. The distributions of ACA are presented in the form hyper/thermophilicmesophilic distribution
 °°The obtained P(t) of the ShapiroWilk test is 0.46 removing 2 outliers; P(t) of the associated ttest = 0.005 removing the outliers
 °°°The obtained P(t) of the ShapiroWilk test is 0.62 removing 3 outliers; P(t) of the associated ttest = 0.001 removing the outliers