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Table 5 Preferred amino acid interactions in CHCs. Hyperthermophilic versus mesophilic proteins of dataset A are compared*

From: "Hot cores" in proteins: Comparative analysis of the apolar contact area in structures from hyper/thermophilic and mesophilic organisms

 

ALA

VAL

PHE

ILE

LEU

ASP

GLU

GLY

LYS

SER

THR

TYR

CYS

ASN

GLN

PRO

MET

ARG

HIS

TRP

XXX

ALA

-2.03

                    

VAL

-0.36

-0.55

                   

PHE

0.85

-0.46

-0.26

                  

ILE

3.07

6.09

3.17

4.33

                 

LEU

-4.00

-1.11

0.42

3.82

-4.56

                

ASP

-1.23

0.05

-0.49

0.88

-0.23

-0.13

               

GLU

-0.83

0.46

0.49

0.04

2.71

-0.13

0.95

              

GLY

-0.60

-0.52

-0.35

0.81

-0.45

-0.51

0.92

0.01

             

LYS

-1.73

-1.03

0.46

2.45

1.13

-0.48

2.37

0.39

0.98

            

SER

-0.87

-0.35

-0.08

1.13

-0.60

-0.16

0.07

-0.81

0.48

0.11

           

THR

-1.48

-0.43

-0.40

0.02

-1.03

0.04

-1.01

0.52

0.29

0.13

0.16

          

TYR

-0.23

1.54

0.17

1.44

-1.51

0.37

-0.19

0.22

-0.49

0.38

-0.08

0.53

         

CYS

-1.76

-1.79

-0.67

-0.57

-3.03

-0.17

-0.01

-0.59

-0.35

-0.77

-0.37

-0.30

-0.12

        

ASN

0.67

0.20

0.01

0.33

-0.82

-0.27

0.22

0.24

0.16

-0.23

-0.56

-0.59

0.06

0.06

       

GLN

-1.19

-0.88

0.12

0.23

-2.61

-0.34

-1.13

-0.55

0.31

-0.56

-1.32

-0.56

-0.16

-0.04

-0.23

      

PRO

0.03

-0.73

0.36

0.27

0.10

0.15

0.71

0.75

0.49

-0.16

-0.32

-0.21

-0.48

0.44

-0.49

0.21

     

MET

-0.85

0.44

-0.08

1.22

-0.23

-0.29

0.79

-0.61

0.31

0.23

0.29

-0.25

-0.57

0.15

-0.23

-0.12

0.04

    

ARG

-0.31

1.08

0.15

1.65

1.01

-0.12

1.51

-0.04

0.10

-0.07

-0.05

0.49

0.05

-0.18

-0.60

0.34

0.43

0.49

   

HIS

-0.50

0.23

-0.13

0.28

-1.55

-0.24

-0.92

0.06

-0.93

-0.11

-0.24

0.16

-0.55

-0.05

-0.02

-0.02

-0.05

-0.14

0.37

  

TRP

0.01

-0.40

-0.19

0.64

0.55

0.20

0.95

-0.11

-0.25

-0.08

-0.06

-0.30

-0.14

-0.48

-0.04

0.25

-0.23

0.46

-0.48

0.21

 

XXX

0.35

0.09

0.39

0.61

0.74

0.22

0.35

0.04

0.09

0.23

0.26

0.23

0.00

0.05

0.09

0.18

0.00

0.06

-0.08

0.09

0.13

  1. * Values are expressed in units of standard deviation from the mean (Z-score). Values ≥ 3.0 are considered statistically significant and are bolded. Mean = 0.00; standard deviation = 0.10.