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Figure 7 | BMC Structural Biology

Figure 7

From: Solution structure of the Legionella pneumophila Mip-rapamycin complex

Figure 7

Detail from the overlay of Mip77–213 and FKBP12 in complex with rapamycin. Solution structure of the Mip-rapamycin complex is shown in blue and the crystal structure of the FKBP12-rapamycin complex in magenta. In FKBP12, F-48 does not directly contribute to binding of rapamycin. Its analogue in Mip, F-153, takes over the function of F-46 in FKBP12, because residue 151 is alanine in Mip.

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