Figure 8

cx [59] conservation in comparative models. Boxplot showing the distribution, relative to seq.id., of the percentage of cleft atoms with different cx values (|Δcx| > 1, see Materials and Methods) between the experimental structure and the model. cx [59], or protrusion index, is an atomic-level shape descriptor that can be used to identify functional regions in proteins. The dashed line represents the auto-model control (see Materials and Methods).