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Figure 4 | BMC Structural Biology

Figure 4

From: Improving the accuracy of template-based predictions by mixing and matching between initial models

Figure 4

Examples illustrating refined structurally variable regions. A. Shown are the backbone ribbon representations of the experimental structure (grey) of CASP7 target T0368 (PDB identifier 2HR2), the refined CF model (red), and the initial comparative prediction (green). The two structurally variable regions (loop 1 and loop 2) of the CF model (red) show more native-like conformations compared to those of the initial model (green), which results in an improvement of 0.6 Å CαRMSD for the CF model. B. Shown are the backbone ribbon representations of the experimental structure (grey) of CASP7 target T0308 (PDB identifier 2H57), the refined CF model (red), and the initial comparative prediction (green). The structurally variable region (indicated by an arrow) of the CF model (red) shows a more native-like conformation compared to that of the initial model (green), which results in an improvement of 0.3 Å CαRMSD for the CF model.

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