Figure 5From: CUSP: an algorithm to distinguish structurally conserved and unconserved regions in protein domain alignments and its application in the study of large length variationsa Structurally conserved regions identified in the globin fold (in pink) by CUSP on independently derived alignments from PASS2 and CE (left and right respectively). b Dwarf and giant domains in the Ferritin superfamily ([1dvba1 (1–147)] and [1mtyd- (15–526)], left and right respectively) show a common conserved core of 4 helices (in brown) surrounding a central Fe atom. Additional lengths in methane monoxygenase hydroxylase, the giant domain, (in green) participate in domain interactions.Back to article page