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Table 1 Description of model types (ALN.X.Y nomenclature)

From: Systematic analysis of the effect of multiple templates on the accuracy of comparative models of protein structure

Model Alignment Template Description
SEQ.2.2 Template1 and Template2 sequences are structurally aligned first. Target sequence is then aligned to both the templates sequence using a pairwise alignment algorithm without altering the structural alignment between the templates. T1 & T2 A two-template model based on the simplest (least accurate) alignment. This model is influenced by the sequences and structures of both templates.
SEQ.2.1 Same as SEQ.2.2 T1 A one-template model based on the simplest (least accurate) alignment between target and both template sequences. This model is influenced by the sequences of both templates but only by the structure of T1.
STR.2.2 Target, Template1 and Template2 sequences are structurally aligned. T1 & T2 A two-template model based on an error-free alignment derived from the structural superposition of the target, T1, and T2.
STR.2.1 Same as STR.2.2 T1 A one-template model based on an error-free alignment derived from the structural superposition of the target, T1, and T2.
  1. Description of different types of models used to evaluate the contribution of the second template in structural complementarity in the context of varying alignment quality. T1 and T2 refer to Template1 and Template2.