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Table 1 Ranking of the poses of references inhibitory molecules (1i-8i and 11i-12i) in the target NF-kappaB p50 both as dimer (p50-p50) and as monomers (p50 A and B).

From: Docking of molecules identified in bioactive medicinal plants extracts into the p50 NF-kappaB transcription factor: correlation with inhibition of NF-kappaB/DNA interactions and inhibitory effects on IL-8 gene expression

Docking protocol 1

p50-p50

p50 (A)

p50 (B)

Cpd.

G-Score

Cpd.

G-Score

Cpd

G-Score

8i

-5.88

8i

-6.06

1i

-6.08

7i

-5.88

7i

-5.83

3i

-5.35

2i

-5.84

11i

-5.20

7i

-5.06

3i

-5.78

1i

-5.07

2i

-4.58

11i

-3.87

2i

-2.79

11i

-3.59

1i

-3.57

3i

-2.77

4i

-1.82

4i

-0.76

4i

> 0

8i

> 0

12i

> 0

12i

> 0

12i

> 0

5i

-

5i

> 0

5i

-

6i

-

6i

> 0

6i

-