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Figure 2 | BMC Structural Biology

Figure 2

From: Type II restriction endonuclease R.Hpy188I belongs to the GIY-YIG nuclease superfamily, but exhibits an unusual active site

Figure 2

A structural model of R.Hpy188I (A and B) compared to its experimentally characterized homologs (C and D). Coordinates of the R.Hpy188I model are available for download from the FTP server ftp://genesilico.pl/iamb/models/R.Hpy188I/ (A) R.Hpy188I with the homology-modeled part colored according to secondary structure (helices in red, strands in yellow, loops in grey) and regions modeled de novo shown in cyan. (B) R.Hpy188I model colored according to the MetaMQAP score. Reliable regions are colored blue, less reliable regions are colored green (predicted deviation from the native structure ~3 Å) unreliable regions are colored yellow to red. (C) GIY-YIG domain in I-TevI (1mk0). (D) GIY-YIG domain in UvrC (1yd0).

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BMC Structural Biology

ISSN: 1472-6807

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