Figure 3From: Type II restriction endonuclease R.Hpy188I belongs to the GIY-YIG nuclease superfamily, but exhibits an unusual active siteSuperposition, in stereo view, of the predicted active site residues of R.Hpy188I (green), UvrC (1yd0; blue) and I-TevI (1mk0; red). A divalent metal ion (Mn2+ in the case of the 1yd0 structure) is shown as a yellow sphere.Back to article page