Figure 5From: Type II restriction endonuclease R.Hpy188I belongs to the GIY-YIG nuclease superfamily, but exhibits an unusual active siteSurface features in the R.Hpy188I model. The orientation is the same as in Figure 2. (A) Sequence conservation: conserved regions are colored purple, variable regions are colored teal, while average regions are white. (B) Electrostatic potential: positively and negatively charged regions are colored in blue and red, respectively.Back to article page