Figure 2From: Structural basis of GC-1 selectivity for thyroid hormone receptor isoformsBleicher2.png. The TR hormone binding site, shown as T3 bound to hTRβ. The regions shown in red, gray and blue correspond to regions I, II and III described in the text. Apolar residues are shown in gray, basic residues in blue (namely His435, Arg316, Arg282 and Arg320) and polar residues in orange (including Asn331).Back to article page