An automatic method for assessing structural importance of amino acid positions

BMC Structural Biology

Table 2 Associations between structural correlations and residue types

Type	Chi-sq.	Significance	N	Category
Functional	602.4	< 4e-15	3201	Uninformative
Intermediate	24.6	< 1e-04	5220	Neutral
Interface	180.52	< 4e-15	2677	Neutral
Buried	261.5	< 4e-15	7033	Informative
Exposed	398.1	< 4e-15	10547	Neutral

Chi-squared values (Chi-sq) with significance levels are shown for each of the five residue types: Buried, intermediate, exposed, functional and interface. See text for definitions. Significance values are corrected for five tests using Bonferroni's correction. The "category" column indicates the direction of correlation overrepresented for that class where probabilities were significant at the 5% level.

ISSN: 1472-6807