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Table 4 Associations between structural correlations and residue types

From: An automatic method for assessing structural importance of amino acid positions

AA Chi-sq. Significance N Category
A 36.7 < 4e-15 3339 Uninformative
C 137.6 < 4e-15 982 Informative
D 48.5 < 5e-10 2373 Neutral
E 58.3 < 4e-12 1934 Uninformative
F 93 < 4e-15 1621 Uninformative
G 33.9 < 4e-15 2830 Informative
H 7.4 > 0.05 1098 Not Significant
I 8.4 > 0.05 1729 Not Significant
K 29.1 < 1e-05 2369 Uninformative
L 52.8 < 1e-10 2812 Informative
M 9 > 0.05 762 Not significant
N 30 < 1e-05 1963 Uninformative
P 49.9 < 1e-10 1540 Informative
Q 12.9 < 0.025 1181 Uninformative
R 37.5 < 2e-07 1419 Uninformative
S 11.6 > 0.05 2172 Not Significant
T 0.6 > 0.05 1926 Not significant
V 21.1 < 1e-03 2441 Neutral
W 38.8 < 1e-07 745 Informative
Y 17.3 < 0.005 1625 Informative
  1. Chi-squared (chi-sq) values with significance levels for structural correlations (see Methods) are shown for each of the twenty amino-acid types. Significance values are corrected for twenty tests using Bonferroni's correction. The "category" column indicates the direction of correlation overrepresented for that class where probabilities were significant at the 5% level.