Figure 1From: Implications of the structure of human uridine phosphorylase 1 on the development of novel inhibitors for improving the therapeutic window of fluoropyrimidine chemotherapyhUPP1 is a dimeric enzyme. In contrast to biophysically analyzed bacterial forms of uridine phosphorylase, human UPP1 is dimeric in solution as analyzed by both calibrated size-exclusion chromatography (blue; x-axis) and multi-angle light scattering analysis (red; y-axis).Back to article page