Figure 9

Combining amino acid side chain displays with pen-and-ink style illustrative renderings. (A) The human growth hormone image from Figure 8 is displayed in a different orientation, and amino acid side chains involved in binding to the growth hormone receptor [50] are shown as a space filling style display colored by amino acid type (the amino acids are F10, F54, E56, I58, R64, Q68, D171, K172, E174, T175, F176, R178, C182, and V185). The α-carbons are also shown. (B) The same as (A), except that the protein is shown as ribbons and the amino acid side chains are shown as a balls and sticks style display. (C) The transmembrane β-barrel protein porin that was shown as a side view in Figure 2A is shown here with an end view of the β-barrel. A loop region (loop 7) that fits inside the β-barrel is highlighted in red. (D) The same as (C), except that the amino acid side chains of loop 7 are shown as a space filling style display and are colored by amino acid type. Loop 7 restricts the size of the channel to a narrow region called the eyelet, which is about 8 angstroms in diameter and 9 angstroms in length [28, 29].