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Figure 1 | BMC Structural Biology

Figure 1

From: Development of an accurate classification system of proteins into structured and unstructured regions that uncovers novel structural domains: its application to human transcription factors

Figure 1

Sequence alignment pattern of a protein with a long ID region. At the top, the domain structure, the sequence of the human androgen receptor (hAR), and a residue number scale are presented. Below them, some of the high-scoring homologues found by a BLAST search conducted with hAR as query against Swiss-Prot are presented, where the solid bars represent aligned segments and the dotted ones do un-aligned segments. The star signifies mammalian orthologues: the N-terminal sections of paralogues, such as the progesterone receptor and the glucocorticoid receptor, cannot be aligned to hAR. The bar representation output of the BLAST server http://blast.ncbi.nlm.nih.gov/ was modified.

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