Figure 6From: Molecular models of human P-glycoprotein in two different catalytic statesResidues potentially involved in the hinge bending motion of TM3–TM4 and TM5–TM6 pairs. Ribbon representation of TM3–TM4 (in blue) and TM5–TM6 (in green). The conserved residues identified by ConSurf (see text) with a potential role in the hinge conformational change upon ATP binding are depicted as red spheres.Back to article page