Figure 6From: Prediction of mono- and di-nucleotide-specific DNA-binding sites in proteins using neural networksROC curves of prediction performance for dinucleotide step contacts of residues. For all dinucleotide contacts evolutionary profiles show a significant improvement on single sequence-based prediction, which is further improved by adding local structure information i.e. secondary structure (SS) and solvent accessibility (ASA) and global amino-acid composition (GAC).Back to article page