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Table 2 Propensity of dinucleotide steps in major and minor groove (most significant residues)

From: Prediction of mono- and di-nucleotide-specific DNA-binding sites in proteins using neural networks

Groove Step H K N Q R Y
Major AA/TT 1.23 0.64 5.41 3.80 2.21 1.18
  AC/GT 2.71 1.09 2.90 1.21 4.14 1.03
  AG/CT 1.72 1.92 2.54 3.21 2.92 1.48
  AT/AT 2.32 0.65 4.95 1.85 2.55 2.10
  CA/TG 1.35 0.26 2.58 0.56 3.40 1.50
  CC/GG 3.66 1.09 1.49 1.00 4.17 0.77
  CG/CG 1.90 1.78 0.46 2.08 5.36 1.10
  GA/TC 2.58 2.83 1.03 0.80 5.14 0.38
  GC/GC 2.34 3.03 1.32 1.08 5.03 0.70
  TA/TA 2.26 0.00 6.48 4.72 0.72 3.19
Minor AA/TT 1.28 1.32 0.45 0.42 8.15 0.00
  AC/GT 1.92 1.97 0.00 0.94 3.53 3.17
  AG/CT 0.00 0.63 2.64 1.86 3.00 1.79
  AT/AT 0.52 1.51 2.66 0.30 3.75 2.38
  CA/TG 0.00 1.13 1.38 1.33 5.79 1.80
  CC/GG 1.91 1.80 2.35 1.49 3.39 2.27
  CG/CG 0.00 2.19 2.41 2.73 2.25 2.38
  GA/TC 0.00 1.26 0.75 2.38 3.62 0.00
  GC/GC 0.00 2.56 1.35 1.92 2.67 1.23
  TA/TA 0.00 3.88 0.00 0.00 4.94 3.65