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Table 2 Propensity of dinucleotide steps in major and minor groove (most significant residues)

From: Prediction of mono- and di-nucleotide-specific DNA-binding sites in proteins using neural networks

Groove

Step

H

K

N

Q

R

Y

Major

AA/TT

1.23

0.64

5.41

3.80

2.21

1.18

 

AC/GT

2.71

1.09

2.90

1.21

4.14

1.03

 

AG/CT

1.72

1.92

2.54

3.21

2.92

1.48

 

AT/AT

2.32

0.65

4.95

1.85

2.55

2.10

 

CA/TG

1.35

0.26

2.58

0.56

3.40

1.50

 

CC/GG

3.66

1.09

1.49

1.00

4.17

0.77

 

CG/CG

1.90

1.78

0.46

2.08

5.36

1.10

 

GA/TC

2.58

2.83

1.03

0.80

5.14

0.38

 

GC/GC

2.34

3.03

1.32

1.08

5.03

0.70

 

TA/TA

2.26

0.00

6.48

4.72

0.72

3.19

Minor

AA/TT

1.28

1.32

0.45

0.42

8.15

0.00

 

AC/GT

1.92

1.97

0.00

0.94

3.53

3.17

 

AG/CT

0.00

0.63

2.64

1.86

3.00

1.79

 

AT/AT

0.52

1.51

2.66

0.30

3.75

2.38

 

CA/TG

0.00

1.13

1.38

1.33

5.79

1.80

 

CC/GG

1.91

1.80

2.35

1.49

3.39

2.27

 

CG/CG

0.00

2.19

2.41

2.73

2.25

2.38

 

GA/TC

0.00

1.26

0.75

2.38

3.62

0.00

 

GC/GC

0.00

2.56

1.35

1.92

2.67

1.23

 

TA/TA

0.00

3.88

0.00

0.00

4.94

3.65